Pharmacokinetics | Drug Metabolism

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Mary
English
College Students
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Summary
Drug metabolism involves converting active drugs into inactive forms for easier excretion. The liver plays a crucial role, utilizing cytochrome P450 enzymes to perform phase one (oxidation, reduction, hydrolysis) and phase two (conjugation) transformations. Factors like genetic polymorphisms, drug interactions, and liver health significantly influence metabolism efficiency and drug efficacy.
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