The Role of Azoles

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John
englanti
Yliopisto-opiskelijat
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Tee videostasi erottuva sekunneissa. Säädä ääntä, kieltä, tyyliä ja kohdeyleisöä juuri haluamallasi tavalla!
Yhteenveto
Azoles are antifungal agents that target fungal cell membranes by inhibiting ergosterol synthesis. They bind to the 14-alpha-dimethylase enzyme, preventing the conversion of lanosterol to ergosterol. This leads to an accumulation of harmful sterols and a depletion of ergosterol, ultimately destabilizing the cell membrane and causing fungal cell death.
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