The Difference between VENLAFAXINE (EFFEXOR) and DESVENLAFAXINE (PRISTIQ) | A Psychiatrist Explains

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Venlafaxine and desvenlafaxine are both SNRIs used as antidepressants, but differ in their mechanisms. Venlafaxine's effects depend on dosage, affecting serotonin and norepinephrine sequentially, leading to various side effects. Desvenlafaxine acts as an SNRI from the start, with a more stable side effect profile, primarily effective in major depressive disorder.
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