Pharmacokinetics | Drug Absorption

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John
Engels
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Professioneel Academisch
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Samenvatting
Pharmacokinetics involves understanding drug absorption, focusing on how drugs enter circulation through various administration routes. Key mechanisms include passive diffusion, facilitated diffusion, active transport, and endocytosis. Factors affecting absorption include pH, blood flow, surface area, and first-pass metabolism. Bioavailability measures the fraction of drug reaching systemic circulation, crucial for effective treatment.
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